蔡高峰，男，1992年出生，浙江諸暨人，博士研究生，碩士研究生導(dǎo)師，江西農(nóng)業(yè)大學(xué)校聘教授。2023年畢業(yè)于南京農(nóng)業(yè)大學(xué)臨床中獸醫(yī)方向，現(xiàn)為中國畜牧獸醫(yī)學(xué)會(huì)中獸醫(yī)學(xué)分會(huì)會(huì)員，江西省微量元素與健康研究會(huì)理事，江西省農(nóng)業(yè)農(nóng)村廳科技特派員。主要研究方向?yàn)橹兴幊煞肿鳛槊庖哒{(diào)控物質(zhì)，增強(qiáng)腸道黏膜免疫應(yīng)答，改善腸道微生物菌群結(jié)構(gòu)和促進(jìn)腸道干細(xì)胞分化、潘氏細(xì)胞抗菌肽分泌的機(jī)制研究，以及中藥提取物作為飼料添加劑在防治細(xì)菌性腹瀉中的“替抗”研究。此外，通過整合納米材料學(xué)與中藥多糖免疫活性進(jìn)行疫苗佐劑設(shè)計(jì)與開發(fā)、保護(hù)性免疫應(yīng)答機(jī)制研究，重點(diǎn)對(duì)口服黏膜佐劑遞送系統(tǒng)進(jìn)行了深入優(yōu)化和研究，并取得了一系列的重要進(jìn)展?，F(xiàn)主持國家自然科學(xué)基金青年項(xiàng)目1項(xiàng)、江西省自然科學(xué)基金青年項(xiàng)目1項(xiàng)、江西省職業(yè)早期青年科技人才培養(yǎng)項(xiàng)目1項(xiàng)，省級(jí)創(chuàng)新創(chuàng)業(yè)項(xiàng)目1項(xiàng)、校教改項(xiàng)目1項(xiàng)，并參與國家自然科學(xué)基金2項(xiàng)。近5年先后發(fā)表SCI學(xué)術(shù)論文20余篇，其中第一作者SCI收錄6篇，作文核心1篇。
E-mail: cgf19920617@163.com
教育經(jīng)歷（從大學(xué)本科開始，按時(shí)間倒排序）：
[1] 2019-09至2023-06，南京農(nóng)業(yè)大學(xué)，臨床獸醫(yī)學(xué)，博士
[2] 2014-09至2017-06，江西農(nóng)業(yè)大學(xué)，預(yù)防獸醫(yī)學(xué)，碩士
[3] 2010-09至2014-06，江西農(nóng)業(yè)大學(xué)，動(dòng)物醫(yī)學(xué)，學(xué)士
工作經(jīng)歷（科研與學(xué)術(shù)工作經(jīng)歷，包括國外訪學(xué)，按時(shí)間倒排序）：
2023.7-至今，江西農(nóng)業(yè)大學(xué)，動(dòng)物科學(xué)技術(shù)學(xué)院，講師（校聘教授）
代表性研究成果和學(xué)術(shù)獎(jiǎng)勵(lì)情況：
[1] Cai, G., Wu, C., Zhu, T., Peng, S., Xu, S., Hu, Y., Liu, Z., Yang, Y., Wang, D. Structure of a Pueraria root polysaccharide and its immunoregulatory activity on T and B lymphocytes, macrophages, and immunosuppressive mice[J]. International Journal of Biological Macromolecules, 2023, 230: 123386. (一作，中科院1區(qū)，Top，IF= 8.2)
[2] Cai, G., Wu, C., Mao, N., Song, Z., Yu, L., Zhu, T., Peng, S., Yang, Y., Liu, Z., & Wang, D. Isolation, purification and characterization of Pueraria lobata polysaccharide and its effects on intestinal function in cyclophosphamide-treated mice[J]. International Journal of Biological Macromolecules, 2022, 218: 356-367. (一作，中科院1區(qū)，Top，IF= 8.2)
[3] Cai, G., Yang, Y., Gu, P., Li, K., Adelijiang, W., Zhu, T., Liu, Z., & Wang, D. The secretion of sIgA and dendritic cells activation in the intestinal of cyclophosphamide-induced immunosuppressed mice are regulated by Alhagi honey polysaccharides[J]. Phytomedicine, 2022, 103: 154232. (一作，中科院1區(qū)，Top，IF= 7.9)
[4] Cai, G., Wu, Y., Wusiman, A., Gu, P., Mao, N., Xu, S., Zhu, T., Feng, Z., Liu, Z., & Wang, D. Alhagi honey polysaccharides attenuate intestinal injury and immune suppression in cyclophosphamide-induced mice[J]. Food & Function, 2021, 12(15): 6863–6877. (一作，中科院1區(qū)，Top，IF= 6.317)
[5] Cai, G., Wusiman, A., Gu, P., Mao, N., Xu, S., Zhu, T., He, J., Liu, Z., & Wang, D. Supplementation of Alhagi honey polysaccharides contributes to the improvement of the intestinal immunity regulating the structure of intestinal flora in mice[J]. Food & Function, 2021, 12(20): 9693–9707. (一作，中科院1區(qū)，Top，IF= 6.317)
[6] Cai, G., Mao, N., Gu, P., Zhu, T., He, J., Peng, S., Yang, Y., Liu, Z., Hu, Y., Wang, D. Effects of Alhagi Honey Polysaccharides as Feed Supplement on Intestine Function and Microbiome, Immune Function, and Growth Performance in Chicken[J]. International Journal of Molecular Sciences, 2022, 23(22): 14332. (一作，中科院2區(qū)，Top，IF= 6.208)
[7] 蔡高峰，毛寧寧，朱天宇，賀瑾，朱少武，薛瑞，雷商商，劉振廣，胡元亮，王德云，刺糖多糖對(duì)雞免疫新城疫疫苗后免疫功能的調(diào)節(jié)作用[J]. 畜牧與獸醫(yī), 2023, 55(02): 129-134. (一作，中文核心期刊)
[8] Wusiman, A., He, J., Cai, G., Zhu, T., Bo, R., Liu, Z., Hu, Y., & Wang, D. Alhagi honey polysaccharides encapsulated into PLGA nanoparticle-based pickering emulsion as a novel adjuvant to induce strong and long-lasting immune responses[J]. International Journal of Biological Macromolecules, 2022, 202: 130–140. (中科院1區(qū)，Top，IF= 8.025)
[9] Gu, P., Cai, G., Yang, Y., Hu, Y., Liu, J., & Wang, D. Polyethylenimine-coated PLGA nanoparticles containing Angelica sinensis polysaccharide promote dendritic cells activation and associated molecular mechanisms[J]. International Journal of Biological Macromolecules, 2022, 207: 559–569. (中科院1區(qū)，Top，IF= 8.025)
[10] Gu, P., Zhang, Y., Cai, G., Liu, Z., Hu, Y., Liu, J., & Wang, D. Administration Routes of Polyethylenimine-Coated PLGA Nanoparticles Encapsulating Angelica Sinensis Polysaccharide Vaccine Delivery System Affect Immune Responses[J]. Molecular pharmaceutics, 2021, 18(6): 2274–2284. (中科院2區(qū)，IF= 5.364)
[11] Gu, P., Wusiman, A., Zhang, Y., Cai, G., Xu, S., Zhu, S., Liu, Z., Hu, Y., Liu, J., & Wang, D. Polyethylenimine-coated PLGA nanoparticles-encapsulated Angelica sinensis polysaccharide as an adjuvant for H9N2 vaccine to improve immune responses in chickens compared to Alum and oil-based adjuvants[J]. Veterinary microbiology, 2020, 251: 108894. (中科院1區(qū)，Top，IF= 3.293)
[12] Shuwen Xu; Zhiyong Wu; Gaofeng Cai; Yue Zhang; Song Peng; Lina Jiao; Zhenguang Liu; Yang Yang; Deyun Wang. Astragalus polysaccharides combined with simvastatin as an immunostimulant enhances the immune adjuvanticity of oil-in-water emulsion and immune responses in mice[J]. Vaccine. 2023, 41(10): 1684-1693. (中科院3區(qū)，IF= 4.169)
[13] Zhang, Yue; Zhu, Tianyu; Xu, Shuwen; Gu, Pengfei; Cai, Gaofeng; Peng, Song; Liu, Zhenguang; Yang, Yang; Hu, Yuanliang; Liu, Jiaguo; Wang, Deyun. Cationic nanoparticles-stabilized vaccine delivery system for the H9N2 vaccine to promote the immune response in chickens. Molecular Pharmaceutics[J]. 2023, 20(3): 1613-1623. (中科院2區(qū)，IF= 5.364)
[14] Peng W, Jiang C, Cai G, Liu L, Guo X, Gao X, Li G, Zheng Z, Liu P, Liu P. Preparation of polyclonal antibody against thrombospondin 2 recombinant protein and its functional verification in pulmonary hypertension syndrome in broilers[J]. International Journal of Biological Macromolecules, 2024, 274: 133284. (中科院2區(qū)，Top，IF= 7.7)
[15] Yang Y, Lv L, Shi S, Cai G, Yu L, Xu S, Zhu T, Su X, Mao N, Zhang Y, Peng S, He J, Liu Z, Wang D. Polysaccharide from walnut green husk alleviates liver inflammation and gluconeogenesis dysfunction by altering gut microbiota in ochratoxin A-induced mice[J]. Carbohydr Polym, 2023, 322:121362.(中科院1區(qū)，Top，IF= 10.7)
[16] Qi Q, Li Y, Ding M, Huang C, Omar SM, Shi Y, Liu P, Cai G, Zheng Z, Guo X, Gao X. Wogonin Inhibits Apoptosis and Necroptosis Induced by Nephropathogenic Infectious Bronchitis Virus in Chicken Renal Tubular Epithelial Cells[J]. International Journal of Molecular Sciences, 2024, 25(15):8194.(中科院3區(qū)，IF=4.9)
[17] Chen Y, Feng C, Huang C, Shi Y, Omar SM, Zhang B, Cai G, Liu P, Guo X, Gao X. Preparation of polyclonal antibodies to chicken P62 protein and its application in nephropathogenic infectious bronchitis virus-infected chickens[J]. International Journal of Biological Macromolecules, 2024, 271:132515. (中科院2區(qū)，Top，IF= 7.7)
[18] Zeng Y, Shi Y, Chen Y, Zhong S, Omar SM, Liu P, Zhuang Y, Cai G, Guo X, Gao X. Preparation of polyclonal antibody to CHOP protein and its application in heat stress of chickens[J]. International Journal of Biological Macromolecules, 2025, 286:138362. (中科院2區(qū)，Top，IF= 7.7)
[19] He J, Zhu T, Mao N, Cai G, Gu P, Song Z, Lu X, Yang Y, Wang D. Cistanche deserticola polysaccharide-functionalized dendritic fibrous nano-silica as oral vaccine adjuvant delivery enhancing both the mucosal and systemic immunity[J]. International Journal of Biological Macromolecules, 2024, 262:129982. (中科院2區(qū)，Top，IF= 7.7)
[20] Liu Z, Tang R, Qi Q, Lin S, Liu P, Cai G, Zheng Z, Guo X, Gao X. Naringenin alleviates heat stress-induced liver injury in Ningdu yellow chickens by decreasing RIPK3 and PDC binding[J]. JOURNAL OF NUTRITIONAL BIOCHEMISTRY. 2025, 140:109894.(中科院2區(qū)，IF= 4.8)
[21] Peng W, Wan G, Cheng S, Li G, Liu L, Chen J, Liu P, Guo X, Gao X, Cai G, Zheng Z, Liu P. Potential role of TRAF2 in pulmonary hypertension in broiler chickens and preparation and specificity analysis of its polyclonal antibody[J]. International Journal of Biological Macromolecules, 2025, 295:139741.(中科院2區(qū)，Top，IF= 7.7)
主持或參加科研項(xiàng)目及人才計(jì)劃項(xiàng)目情況（按時(shí)間倒排序）：
[1] 國家自然科學(xué)基金委員會(huì)，青年科學(xué)基金項(xiàng)目（C類）[原青年科學(xué)基金項(xiàng)目]，32402938，葛根多糖調(diào)控仔豬腸道潘氏細(xì)胞生成溶菌酶預(yù)防ETEC感染的機(jī)制研究，2025-01-01至2027-12-31，30萬元，在研，主持；
[2] 江西省科技計(jì)劃項(xiàng)目，自然（青年）科學(xué)基金，20242BAB20314，葛根多糖-樹枝狀介孔二氧化硅增強(qiáng)PEDV口服疫苗黏膜免疫效果及其作用機(jī)制研究，2024-06-01至2027-05-31，10萬元，在研，主持；
[3] 江西省科技計(jì)劃項(xiàng)目，職業(yè)早期青年科技人才培養(yǎng)項(xiàng)目，20244BCE52047，基于腸道微生物研究葛根多糖調(diào)控仔豬腸道抗菌肽分泌的作用機(jī)制，2024-12-17至2029-12-31，20萬元，在研，主持；
[4] 江西農(nóng)業(yè)大學(xué)人才引進(jìn)啟動(dòng)項(xiàng)目，30萬，在研，主持；
[5] 國家自然科學(xué)基金委員會(huì)，地區(qū)項(xiàng)目，32460850，瘤胃微生物與宿主互作介導(dǎo)葛根素促進(jìn)肉羊肌內(nèi)脂肪沉積的機(jī)理，2025-01-01至2028-12-31，39萬元，在研，參與；
[6] 國家自然科學(xué)基金委員會(huì), 面上項(xiàng)目, 32072905, 中藥多糖Pickering乳液的佐劑活性及其作用機(jī)理的研究, 2021-01-01 至 2024-12-31, 58萬元, 在研, 參與。
